3-Methyl-1-Phenyl-5-Pyrazolone; 3-Methyl-1-Phenyl-2-Pyrazoline-5-One; Edaravone CAS: 89-25-8 High-Purity 99%; High-Quality Edaravone

• Customization: Available
• CAS No.: 89-25-8
• Formula: C10h10n2o
• Model NO.: Organic Intermediate
• EINECS: 201-891-0
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Colour: White
• Certifications: SGS; ISO; GMP; FDA; cGMP; Cos
• Sample: Available
• Documents: Moa;MSDS;COA;Ros;Hnmr, Cnmr, Ms
• Tp: Available
• Transport Package: 1kg, 25kg Bag; Drum
• Specification: Inhouse; Customer Standards
• Trademark: High-quality Products
• Origin: China
• HS Code: 2933199090
• Production Capacity: 60ton/Year

Product Description

3-methyl-1-phenyl-5-pyrazolone; CAS: 89-25-8

Product Description

3-methyl-1-phenyl-5-pyrazolone;
3-Methyl-1-phenyl-2-pyrazoline-5-one;
Edaravone CAS: 89-25-8


White to Off-White Crystalline Powder.
Purity: 99%
Storage Conditions: Normal temperature, Sealed, Cool and Dry.

Instuction:

Edaravone  is a nootropic and neuroprotective agent used for the purpose of aiding neurological recovery following acute brain ischemia and subsequent cerebral infarction. It acts as a potent antioxidant and strongly scavenges free radicals, protecting against oxidative stress and neuronal apoptosis. It has been marketed solely in Japan by Mitsubishi Pharma since 2001. It is also marketed in India by Edinburgh Pharmaceuticals by the brand name Arone.
On June 26, 2015, Mitsubishi Tanabe Pharma Corporation announced it has received approval to market Radicut for treatment of ALS in Japan. The phase III clinical trial began in 2011 in Japan. The company was awarded Orphan Drug Designation for Radicut by the FDA and EU in 2015. Radicut is an intravenous drug and administrated 14 days followed by 14 days drug holiday.
The biotech company Treeway is developing an oral formulation of edaravone (TW001) and is currently in clinical development. Treeway was awarded orphan drug designation for edaravone by the EMA in November 2014 and FDA in January 2015.
Edaravone has been shown to attenuate methamphetamine- and 6-OHDA-induced dopaminergic neurotoxicity in the striatum and substantia nigra, and does not affect methamphetamine-induced dopamine release or hyperthermia. It has also been demonstrated to protect against MPTP-mediated dopaminergic neurotoxicity to the substantia nigra, though notably not to the striatum.

 

 

Certifications

Our manufacturer has introduced ISO9001 quality management system certification, realizing the whole process control through product design, raw 
material procurement, production process, quanlity assurance, product sales to after service; 

Our manufacturer has fully implemented GMP/FDA/CEP management, GMP/FDA/CEP certifications are available.

Our manufactuer always takes innovation as the core, and attaches great importance to the improvement of its R & D comprehensive strength.
 

 

Our Advantages

1. We can offer you sample for testing.
2. We can pack the material as per your requirement.
3. We can provide you TP documents along shipment.
4. We can accept your audit if necessary near future.
5. We can offer the material as per your specification.
6. We can customize the product as per your specification.
7. We can arrange shipment professional and efficient.