Hesperetin
CAS: 520-33-2
Chemical name: 5,7,3'-trihydroxy-4'-methoxyflavanone
The source of the plant: Citrus Aurantium L.
CAS: 520-33-2
Molecular formula: C16H14O6
Molecular weight: 302.29
Main specification: 95% test by HPLC
Appearance: straw yellow needle crystalline powder
Pharmacology function: Hesperetin is a citrus flavonoid that has been reported to lower plasma cholesterol. Hesperetin reduces the transcription of ACAT-2 mRNA in HepG2 cells and reduces ApoB protein synthesis in a dose-dependent manner. The EC50 for these responses is approximately 50 µM.1 Hesperetin also inhibits histamine release from IgE-challenged RBL-2H3 cells, with a potency comparable to the commercial anti-allergy drug azelastine.
It has anti-lipolysis action and can inhibit proliferation of tumor. As 3-hydroxysteroid dehydrogenase inhibitor, its activity is better than that of aspirin. Asweak aldose reductase inhibitor, it can promote extracorporeal cells of rat lungto be synthesized with DNA. It can be used as plant accelerant with its anti-bacteria and anti-virus activities.
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